Staff & Leadership

Larry Moulton, PhD, MS

Larry Moulton, PhD, MS - Photo

Biography

Professor                            
Department of International Health, Bloomberg School of Public Health
The Johns Hopkins University

Research Interests

International Health, Biostatistics, Statistical Epidemiology, Longitudinal Data, Bioassay, Cluster Randomized Trials, Vaccine Safety, Vaccine Effectiveness, Vitamin A, HIV/AIDS, Landmines

Methods of Expertise

My work in HIV began in the early 1990s when I started working for the Johns Hopkins University as a statistician for HIV epidemiologic studies in Haiti. Since then, much of my HIV work has been in conjunction with tuberculosis research. I have been the principal statistician where I was involved in all phases of design, conduct, and analysis on a number of HIV and TB related studies (i.e., studies of the 14,000+ mother-infant pairs in the ZVITAMBO project in Zimbabwe, the male circumcision trial in Uganda, and the rifapentine and extended INH prophylaxis studies for HIV-related TB in Soweto). In addition, I ran the Biostatistics Core of CREATE, a consortium of large TB community-based studies in HIV-endemic areas. My long-time focus on statistical methods for correlated data have led to me being involved in designing a number of community randomized field trials of HIV-related interventions.

Services Available to CFAR Investigators

I have extensive experience in helping researchers focus their research concepts, in identifying appropriate methods for sample size calculations, in carrying out balanced randomization schemes, and in providing analytic solutions to complicated data situations.

Sample Papers

  1. Solomon SS, Solomon S, McFall AM, Srikrishnan AK, Anand S, Verma V, Vasudevan CK, Balakrishnan P, Ogburn EL, Moulton LH, Kumar MS, Sachdeva KS, Laeyendecker O, Celentano DD, Lucas GM, Mehta SH, Indian National Collaboration on AIDS Study. Integrated HIV Testing, Prevention, and Treatment Intervention for Key Populations in India: a Cluster-randomised Trial. Lancet HIV 2019;6(5):e283-e296. PMC6524776
  2. Evans C, Chasekwa B, Ntozini R, Majo FD, Mutasa K, Tavengwa N, Mutasa B, Mbuya MNN, Smith LE, Stoltzfus RJ, Moulton LH, Humphrey JH, Prendergast AJ, SHINE Trial Team. Mortality, HIV transmission and growth in children exposed to HIV in rural Zimbabwe. Clin Infect Dis 2020 [epub ahead of print]
  3. Ntozini R, Chandna J, Evans C, Chasekwa B, Majo FD, Kandawasvika G, Tavengwa NV, Mutasa B, Mutasa K, Moulton LH, Humphrey JH, Gladstone MJ, Prendergast AJ, SHINE Trial Team. Early child development in children who are HIV-exposed uninfected compared to children who are HIV-unexposed: observational sub-study of a cluster-randomized trial in rural Zimbabwe. J Int AIDS Soc 2020;23(5):e25456. PMC7318086