Administrative Supplement

NIH Administrative Supplements

The CFAR Program at the National Institutes of Health (NIH) invites applications from currently funded CFARs that are eligible for administrative supplements in the following projects/areas of scientific interest:

1. Promoting Viral Suppression in Health Disparity Populations Engaged in HIV Care in Rural Communities
2. HIV Healthcare Systems and Differentiated Care Approaches to Improve Viral Suppression
3. Elucidating Metabolic Consequences of PrEP and ART
4. Obesogenic Mechanisms During HIV Infection
5. Innovative Technologies for Basic Research on HIV and Comorbidities
6. Equipment for CFAR Core(s)
7. Inter-CFAR Meeting
8. Tuberculosis Research (supported by Division of Microbiology and Infectious Diseases (DMID), NIAID –TB mono-infection studies allowed)

Supplement awards are for up to one year. 

The funding amount varies per topic listed above, see the supplement announcement for details.

The CFAR Developmental Core and Executive Committee will select projects to be developed into a full proposal for submission to the NIH.

Each CFAR may submit more than one application in topics 1-5 BUT no more than four total applications per CFAR.
CFARs can submit one application each to the equipment and TB topics. 
Each inter-CFAR group is permitted to submit one meeting application.
The deadline for applications to be received at NIAID is May 24, 2019.
The earliest anticipated start date is 7/01/19 but may be delayed due to administrative issues.

Topics 1 and 2 must be responsive to the overall Ending the HIV Epidemic (EtHE): A Plan for America initiative which is focused on four key pillars  (Diagnose, Treat, Protect, and Respond).  For additional information and background on the EtHE initiative, please refer to the special CFAR/ARC announcement (released on March 4, 2019).


The purpose of this administrative supplement opportunity is to support innovative research projects, inter-CFAR meetings, and shared instrumentation that address key gaps in HIV/AIDS and will advance the field. This opportunity should build research capacity and be consistent with the recent NIH HIV/AIDS research priorities (NOT-OD-15-137).


Project directors are restricted to early career investigators who have never received an R-series, R01-equivalent or U-series research grants.  Established investigators in non-HIV fields who have never received an NIH research award for HIV/AIDS studies are also eligible (except for the TB topic). Established investigators can be the project leaders for the core equipment and inter-CFAR meeting topics.

Studies that are a continuation of previously funded CFAR supplements or funded NIH applications that do not address new specific aims are not eligible for funding under this announcement. Additionally, a proposed supplement application that is linked to a proposed application not yet funded is not eligible for funding under this announcement.

The CFAR may not fund studies involving new drugs, treatments, or devices, or off-label use of a licensed drug (this includes healthy volunteer studies where drugs are administered).
The CFAR may not fund clinical research studies that include randomization to one or more intervention to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes.
Studies involving human subjects may be subject to additional NIH review prior to initiating the study, which may cause delays. Similarly, for studies with any foreign component, additional NIH review and approval is required prior to the initiation of any study procedures. More information can be found here.


Instructions for Application

Please submit a one page Letter of Intent to no later than April 8th, 2019, 5:oo pm (EST). The LOI should include:

Application title
List of investigators
Scientific Area of Interest
Summary of rationale and approach

Please see the Supplement Announcement for full details on the award descriptions and application instructions.

The CFAR Grant Development and Implementation Toolkit is a great resource that is designed to assist in the completion of HIV related grant submissions and to support the implementation of awarded grants. Click here to access the toolkit.

Any questions about the awards or the application process can be directed to